Role of microRNA221 in regulating normal mammary epithelial hierarchy and breast cancer stem-like cells

Increasing evidence suggests that lineage specific subpopulations and stem-like cells exist in normal and malignant breast tissues. Epigenetic mechanisms maintaining this hierarchical homeostasis remain to be investigated. In this study, we found the level of microRNA221 (miR-221) was higher in stem...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Ke, Jia, Zhao, Zhiju, Hong, Su-Hyung, Bai, Shoumin, He, Zhen, Malik, Fayaz, Xu, Jiahui, Zhou, Lei, Chen, Weilong, Martin-Trevino, Rachel, Wu, Xiaojian, Lan, Ping, Yi, Yongju, Ginestier, Christophe, Ibarra, Ingrid, Shang, Li, McDermott, Sean, Luther, Tahra, Clouthier, Shawn G., Wicha, Max S., Liu, Suling
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414148/
https://ncbi.nlm.nih.gov/pubmed/25686829
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