Cyclosporin A differentially inhibits multiple steps in VEGF induced angiogenesis in human microvascular endothelial cells through altered intracellular signaling

The immunosuppressive agent cyclosporin A (CsA), a calcineurin inhibitor which blocks T cell activation has provided the pharmacologic foundation for organ transplantation. CsA exerts additional effects on non-immune cell populations and may adversely effect microvascular endothelial cells, contribu...

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Detalhes bibliográficos
Main Authors: Rafiee, Parvaneh, Heidemann, Jan, Ogawa, Hitoshi, Johnson, Nathan A, Fisher, Pamela J, Li, Mona S, Otterson, Mary F, Johnson, Christopher P, Binion, David G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC441414/
https://ncbi.nlm.nih.gov/pubmed/15175101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-2-3
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