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Paradoxical exacerbation of neuronal injury in reperfused stroke despite improved blood flow and reduced inflammation in early growth response-1 gene-deleted mice

OBJECTIVES: Early growth response gene-1 (Egr-1) coordinates the rapid upregulation of diverse inflammatory and coagulation-related genes following ischemia/reperfusion. Genetic deletion of Egr-1 results in attenuated post-ischemic injury in diverse tissue systems. In the present study, we utilized...

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Bibliografiska uppgifter
I publikationen:Neurol Res
Huvudupphovsmän: Ducruet, Andrew F, Sosunov, Sergey A, Visovatti, Scott H, Petrovic-Djergovic, Danica, Mack, William J, Connolly, E Sander, Pinsky, David J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414049/
https://ncbi.nlm.nih.gov/pubmed/21756551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/1743132810Y.0000000022
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