AS03-Adjuvanted, Very-Low-Dose Influenza Vaccines Induce Distinctive Immune Responses Compared to Unadjuvanted High-Dose Vaccines in BALB/c Mice

During the 2009–2010 influenza pandemic, an adjuvanted, dose-sparing vaccine was recommended for most Canadians. We hypothesize that differences exist in the responses to AS03-adjuvanted, low antigen (Ag) dose versus unadjuvanted, full-dose vaccines. We investigated the relationship between Ag dose...

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Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: Yam, Karen K., Gupta, Jyotsana, Winter, Kaitlin, Allen, Elizabeth, Brewer, Angela, Beaulieu, Édith, Mallett, Corey P., Burt, David S., Ward, Brian J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2015
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413846/
https://ncbi.nlm.nih.gov/pubmed/25972874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00207
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