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Deficient Autophagy Results in Mitochondrial Dysfunction and FSGS

FSGS is a heterogeneous fibrosing disease of the kidney, the cause of which remains poorly understood. In most cases, there is no effective treatment to halt or retard progression to renal failure. Increasing evidence points to mitochondrial dysfunction and the generation of reactive oxygen species...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Kawakami, Takahisa, Gomez, Ivan G., Ren, Shuyu, Hudkins, Kelly, Roach, Allie, Alpers, Charles E., Shankland, Stuart J., D’Agati, Vivette D., Duffield, Jeremy S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413752/
https://ncbi.nlm.nih.gov/pubmed/25406339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013111202
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