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Top2a identifies and provides epigenetic rationale for novel combination therapeutic strategies for aggressive prostate cancer

Progression of aggressive prostate cancers (PCa) with androgen receptor splice variants or neuroendrocrine features is currently untreatable in the clinic. Therefore novel therapies are urgently required. We conducted RNA-seq using tumors from a unique murine transplant mouse model which spontaneous...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Kirk, Jason S., Schaarschuch, Kevin, Dalimov, Zafardjan, Lasorsa, Elena, Ku, ShengYu, Ramakrishnan, Swathi, Hu, Qiang, Azabdaftari, Gissou, Wang, Jianmin, Pili, Roberto, Ellis, Leigh
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413643/
https://ncbi.nlm.nih.gov/pubmed/25605014
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