Adhesion glycoprotein CD44 functions as an upstream regulator of a network connecting ERK, AKT and Hippo-YAP pathways in cancer progression

Targeted therapies are considered to be the future of cancer treatment. However, the mechanism through which intracellular signaling pathways coordinate to modulate oncogenesis remains to be elucidated. In this study, we describe a novel crosstalk among ERK, AKT and Hippo-YAP pathways, with CD44 as...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Yu, Shiyi, Cai, Xiuxiu, Wu, Chenxi, Wu, Lele, Wang, Yuzhi, Liu, Yan, Yu, Zhenghong, Qin, Sheng, Ma, Fei, Thiery, Jean Paul, Chen, Liming
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413630/
https://ncbi.nlm.nih.gov/pubmed/25605020
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