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Adhesion glycoprotein CD44 functions as an upstream regulator of a network connecting ERK, AKT and Hippo-YAP pathways in cancer progression

Targeted therapies are considered to be the future of cancer treatment. However, the mechanism through which intracellular signaling pathways coordinate to modulate oncogenesis remains to be elucidated. In this study, we describe a novel crosstalk among ERK, AKT and Hippo-YAP pathways, with CD44 as...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Yu, Shiyi, Cai, Xiuxiu, Wu, Chenxi, Wu, Lele, Wang, Yuzhi, Liu, Yan, Yu, Zhenghong, Qin, Sheng, Ma, Fei, Thiery, Jean Paul, Chen, Liming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413630/
https://ncbi.nlm.nih.gov/pubmed/25605020
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