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Structure of CARDS toxin, a unique ADP-ribosylating and vacuolating cytotoxin from Mycoplasma pneumoniae

Mycoplasma pneumoniae (Mp) infections cause tracheobronchitis and “walking” pneumonia, and are linked to asthma and other reactive airway diseases. As part of the infectious process, the bacterium expresses a 591-aa virulence factor with both mono-ADP ribosyltransferase (mART) and vacuolating activi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Becker, Argentina, Kannan, T. R., Taylor, Alexander B., Pakhomova, Olga N., Zhang, Yanfeng, Somarajan, Sudha R., Galaleldeen, Ahmad, Holloway, Stephen P., Baseman, Joel B., Hart, P. John
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413325/
https://ncbi.nlm.nih.gov/pubmed/25848012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420308112
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