Structure of CARDS toxin, a unique ADP-ribosylating and vacuolating cytotoxin from Mycoplasma pneumoniae

Mycoplasma pneumoniae (Mp) infections cause tracheobronchitis and “walking” pneumonia, and are linked to asthma and other reactive airway diseases. As part of the infectious process, the bacterium expresses a 591-aa virulence factor with both mono-ADP ribosyltransferase (mART) and vacuolating activi...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Becker, Argentina, Kannan, T. R., Taylor, Alexander B., Pakhomova, Olga N., Zhang, Yanfeng, Somarajan, Sudha R., Galaleldeen, Ahmad, Holloway, Stephen P., Baseman, Joel B., Hart, P. John
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413325/
https://ncbi.nlm.nih.gov/pubmed/25848012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420308112
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