Compromised peroxisomes in idiopathic pulmonary fibrosis, a vicious cycle inducing a higher fibrotic response via TGF-β signaling

Idiopathic pulmonary fibrosis (IPF) is a devastating disease, and its pathogenic mechanisms remain incompletely understood. Peroxisomes are known to be important in ROS and proinflammatory lipid degradation, and their deficiency induces liver fibrosis. However, altered peroxisome functions in IPF pa...

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Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Oruqaj, Gani, Karnati, Srikanth, Vijayan, Vijith, Kotarkonda, Lakshmi Kanth, Boateng, Eistine, Zhang, Wenming, Ruppert, Clemens, Günther, Andreas, Shi, Wei, Baumgart-Vogt, Eveline
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2015
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PNAS Plus
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413321/
https://ncbi.nlm.nih.gov/pubmed/25848047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415111112
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