Synthesis and in Vitro Antiproliferative Evaluation of Some B-norcholesteryl Benzimidazole and Benzothiazole Derivatives

Taking orostanal (a compound from a Japanese marine sponge, Stelletta hiwasaensis) as a lead compound, some novel B-norcholesteryl benzimidazole and benzothiazole derivatives were synthesized. The antiproliferative activity of the compounds against human cervical carcinoma (HeLa), human lung carcino...

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Veröffentlicht in:Mar Drugs
Hauptverfasser: Cui, Jianguo, Qi, Binbin, Gan, Chunfang, Liu, Zhipin, Huang, Hu, Lin, Qifu, Zhao, Dandan, Huang, Yanmin
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413222/
https://ncbi.nlm.nih.gov/pubmed/25913705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md13042488
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