Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases.

c-Jun transcriptional activity is augmented by expression of oncogenic Ras and Raf proteins. This study demonstrates a direct correlation between Ras transforming activity and c-Jun activation, supporting an important role for c-Jun in transformation by Ras. Since we observed that Ras activated c-Ju...

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Detalhes bibliográficos
Main Authors: Westwick, J K, Cox, A D, Der, C J, Cobb, M H, Hibi, M, Karin, M, Brenner, D A
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC44131/
https://ncbi.nlm.nih.gov/pubmed/8016110
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