Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases.
c-Jun transcriptional activity is augmented by expression of oncogenic Ras and Raf proteins. This study demonstrates a direct correlation between Ras transforming activity and c-Jun activation, supporting an important role for c-Jun in transformation by Ras. Since we observed that Ras activated c-Ju...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1994
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44131/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8016110/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.13.6030 |
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