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Decreased osteogenesis of adult mesenchymal stem cells by reactive oxygen species under cyclic stretch: a possible mechanism of age related osteoporosis

Age related defect of the osteogenic differentiation of mesenchymal stem cells (MSCs) plays a key role in osteoporosis. Mechanical loading is one of the most important physical stimuli for osteoblast differentiation. Here, we compared the osteogenic potential of MSCs from young and adult rats under...

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Dettagli Bibliografici
Pubblicato in:Bone Res
Autori principali: Tan, Jiali, Xu, Xin, Tong, Zhongchun, lin, Jiong, Yu, Qiujun, Lin, Yao, Kuang, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413016/
https://ncbi.nlm.nih.gov/pubmed/26273536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/boneres.2015.3
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