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Is Bax/Bcl-2 Ratio Considered as a Prognostic Marker with Age and Tumor Location in Colorectal Cancer?

BACKGROUND: Bax and Bcl-2 are the major members of Bcl-2 family whose play a key role in tumor progression or inhibition of intrinsic apoptotic pathway triggered by mitochondrial dysfunction. Therefore, the balance between pro- and anti-apoptotic members of this family can determine the cellular fat...

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Pubblicato in:Iran Biomed J
Autori principali: Khodapasand, Ehsan, Jafarzadeh, Narges, Farrokhi, Farid, Kamalidehghan, Behnam, Houshmand, Massoud
Natura: Artigo
Lingua:Inglês
Pubblicazione: Pasteur Institute of Iran 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412916/
https://ncbi.nlm.nih.gov/pubmed/25864810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6091/ibj.1366.2015
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