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Large-Scale Analysis of Association Between GDF5 and FRZB Variants and Osteoarthritis of the Hip, Knee, and Hand

OBJECTIVE: GDF5 and FRZB have been proposed as genetic loci conferring susceptibility to osteoarthritis (OA); however, the results of several studies investigating the association of OA with the rs143383 polymorphism of the GDF5 gene or the rs7775 and rs288326 polymorphisms of the FRZB gene have bee...

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Publicado en:Arthritis Rheum
Main Authors: Evangelou, Evangelos, Chapman, Kay, Meulenbelt, Ingrid, Karassa, Fotini B., Loughlin, John, Carr, Andrew, Doherty, Michael, Doherty, Sally, Gómez-Reino, Juan J., Gonzalez, Antonio, Halldorsson, Bjarni V., Hauksson, Valdimar B., Hofman, Albert, Hart, Deborah J., Ikegawa, Shiro, Ingvarsson, Thorvaldur, Jiang, Qing, Jonsdottir, Ingileif, Jonsson, Helgi, Kerkhof, Hanneke J. M., Kloppenburg, Margreet, Lane, Nancy E., Li, Jia, Lories, Rik J., van Meurs, Joyce B. J., Näkki, Annu, Nevitt, Michael C., Rodriguez-Lopez, Julio, Shi, Dongquan, Slagboom, P. Eline, Stefansson, Kari, Tsezou, Aspasia, Wallis, Gillian A., Watson, Christopher M., Spector, Tim D., Uitterlinden, Andre G., Valdes, Ana M., Ioannidis, John P. A.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412885/
https://ncbi.nlm.nih.gov/pubmed/19479880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24524
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