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Population pharmacogenetic-based pharmacokinetic modeling of efavirenz, 7-hydroxy- and 8-hydroxyefavirenz
OBJECTIVES: The purpose of this study was to determine the demographic and pharmacogenetic covariates that influence the disposition of efavirenz (EFV) and its major metabolites. Methods: A population pharmacokinetic (PK) model was developed from a randomized, cross-over, drug-interaction study in h...
Gorde:
| Argitaratua izan da: | J Clin Pharmacol |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2013
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4412845/ https://ncbi.nlm.nih.gov/pubmed/24142869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.208 |
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