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ADAR2-dependent GluA2 editing regulates cocaine seeking
Activation of AMPA receptors in the nucleus accumbens is necessary for the reinstatement of cocaine-seeking behavior, an animal model of drug craving and relapse. AMPA receptors are tetrameric protein complexes that consist of GluA1-GluA4 subunits, of which GluA2 imparts calcium permeability. Adenos...
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Publicado no: | Mol Psychiatry |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4412769/ https://ncbi.nlm.nih.gov/pubmed/25349168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2014.134 |
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