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Mutation of SH2B3 (LNK), a GWAS candidate for hypertension, attenuates Dahl SS hypertension via inflammatory modulation

Human genome wide association studies (GWAS) have linked SH2B3 (LNK) to hypertension and renal disease, though little experimental investigation has been done to verify a role for SH2B3 in these pathologies. SH2B3, a member of the SH2B adaptor protein family, is an intracellular adaptor protein that...

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Detaylı Bibliyografya
Yayımlandı:	Hypertension
Asıl Yazarlar:	Rudemiller, Nathan P., Lund, Hayley, Priestley, Jessica R. C., Endres, Bradley T., Prokop, Jeremy W., Jacob, Howard J., Geurts, Aron M., Cohen, Eric P., Mattson, David L.
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	2015
Konular:	Article
Online Erişim:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4412596/ https://ncbi.nlm.nih.gov/pubmed/25776069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04736
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!

Mutation of SH2B3 (LNK), a GWAS candidate for hypertension, attenuates Dahl SS hypertension via inflammatory modulation

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