Role of NKG2D, DNAM-1 and natural cytotoxicity receptors in cytotoxicity toward rhabdomyosarcoma cell lines mediated by resting and IL-15-activated human natural killer cells

Children with advanced stages (relapsed/refractory and stage IV) of rhabdomyosarcoma (RMS) have a poor prognosis despite intensive chemotherapy and autologous stem cell rescue, with 5-year survival rates ranging from 5 to 35 %. Development of new, additional treatment modalities is necessary to impr...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Boerman, Gerharda H., van Ostaijen-ten Dam, Monique M., Kraal, Kathelijne C. J. M., Santos, Susy J., Ball, Lynne M., Lankester, Arjan C., Schilham, Marco W., Egeler, R. Maarten, van Tol, Maarten J. D.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412555/
https://ncbi.nlm.nih.gov/pubmed/25854581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-015-1657-9
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