Hyperglycemia and redox status regulate RUNX2 DNA-binding and an angiogenic phenotype in endothelial cells

Angiogenesis is regulated by hyperglycemic conditions, which can induce cellular stress responses, reactive oxygen species (ROS), and anti-oxidant defenses that modulate intracellular signaling to prevent oxidative damage. The RUNX2 DNA-binding transcription factor is activated by a glucose-mediated...

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Détails bibliographiques
Publié dans:Microvasc Res
Auteurs principaux: Mochin, Maria T., Underwood, Karen F., Cooper, Brandon, McLenithan, John C., Pierce, Adam D., Nalvarte, Cesar, Arbiser, Jack, Karlsson, Anna I., Moise, Alexander R., Moskovitz, Jackob, Passaniti, Antonino
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412363/
https://ncbi.nlm.nih.gov/pubmed/25283348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mvr.2014.09.008
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