Sequence-independent induction of Sp1 transcription factor activity by phosphorothioate oligodeoxynucleotides.

Modified analogues of antisense oligodeoxynucleotides (ODNs), particularly phosphorothioates ([S]ODNs), have been extensively used to inhibit gene expression. The potential sequence specificity of antisense oligomers makes them attractive as molecular drugs for human diseases. The use of antisense [...

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Main Authors: Perez, J R, Li, Y, Stein, C A, Majumder, S, van Oorschot, A, Narayanan, R
格式: Artigo
語言:Inglês
出版: 1994
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC44116/
https://ncbi.nlm.nih.gov/pubmed/8016096
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