Sequence-independent induction of Sp1 transcription factor activity by phosphorothioate oligodeoxynucleotides.

Modified analogues of antisense oligodeoxynucleotides (ODNs), particularly phosphorothioates ([S]ODNs), have been extensively used to inhibit gene expression. The potential sequence specificity of antisense oligomers makes them attractive as molecular drugs for human diseases. The use of antisense [...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Perez, J R, Li, Y, Stein, C A, Majumder, S, van Oorschot, A, Narayanan, R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44116/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8016096/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.13.5957
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