Mechanism for phosphoinositide selectivity and activation of TRPV1 ion channels

Although PI(4,5)P(2) is believed to play an essential role in regulating the activity of numerous ion channels and transporters, the mechanisms by which it does so are unknown. Here, we used the ability of the TRPV1 ion channel to discriminate between PI(4,5)P(2) and PI(4)P to localize the region of...

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Udgivet i:J Gen Physiol
Main Authors: Ufret-Vincenty, Carmen A., Klein, Rebecca M., Collins, Marcus D., Rosasco, Mario G., Martinez, Gilbert Q., Gordon, Sharona E.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2015
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411251/
https://ncbi.nlm.nih.gov/pubmed/25918361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511354
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