The Phosphoinositide 3-Kinase p110α Isoform Regulates Leukemia Inhibitory Factor Receptor Expression via c-Myc and miR-125b to Promote Cell Proliferation in Medulloblastoma

Medulloblastoma (MB) is the most common malignant brain tumor in childhood and represents the main cause of cancer-related death in this age group. The phosphoinositide 3-kinase (PI3K) pathway has been shown to play an important role in the regulation of medulloblastoma cell survival and proliferati...

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Udgivet i:PLoS One
Main Authors: Salm, Fabiana, Dimitrova, Valeriya, von Bueren, André O., Ćwiek, Paulina, Rehrauer, Hubert, Djonov, Valentin, Anderle, Pascale, Arcaro, Alexandre
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411098/
https://ncbi.nlm.nih.gov/pubmed/25915540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123958
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