Pachymic Acid Inhibits Growth and Induces Apoptosis of Pancreatic Cancer In Vitro and In Vivo by Targeting ER Stress

Pachymic acid (PA) is a purified triterpene extracted from medicinal fungus Poria cocos. In this paper, we investigated the anticancer effect of PA on human chemotherapy resistant pancreatic cancer. PA triggered apoptosis in gemcitabine-resistant pancreatic cancer cells PANC-1 and MIA PaCa-2. Compar...

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Foilsithe in:PLoS One
Main Authors: Cheng, Shujie, Swanson, Kristen, Eliaz, Isaac, McClintick, Jeanette N., Sandusky, George E., Sliva, Daniel
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2015
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411097/
https://ncbi.nlm.nih.gov/pubmed/25915041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122270
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