TNFA Haplotype Genetic Testing Improves HLA in Estimating the Risk of Celiac Disease in Children

BACKGROUND: TNF-α and IFN-γ play a role in the development of mucosal damage in celiac disease (CD). Polymorphisms of TNFA and IFNG genes, as well as of the TNFRSF1A gene, encoding the TNF-α receptor 1, might underlie different inter-individual disease susceptibility over a common HLA risk backgroun...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rossi, Elisa, Basso, Daniela, Zambon, Carlo-Federico, Navaglia, Filippo, Greco, Eliana, Pelloso, Michela, Artuso, Serena, Padoan, Andrea, Pescarin, Matilde, Aita, Ada, Bozzato, Dania, Moz, Stefania, Cananzi, Mara, Guariso, Graziella, Plebani, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411089/
https://ncbi.nlm.nih.gov/pubmed/25915602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123244
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