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Converging mechanisms in ALS and FTD: Disrupted RNA and protein homeostasis

Breakthrough discoveries identifying common genetic causes for amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) have transformed our view of these disorders. They share unexpectedly similar signatures, including dysregulation in common molecular players including TDP-43, FUS/TLS...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neuron
Main Authors: Ling, Shuo-Chien, Polymenidou, Magdalini, Cleveland, Don W.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411085/
https://ncbi.nlm.nih.gov/pubmed/23931993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.07.033
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