Effects of Antiepileptic Drug Monotherapy on One-Carbon Metabolism and DNA Methylation in Patients with Epilepsy

PURPOSE: The aim of this study was to compare the serum levels of one-carbon metabolism (OCM) nutrients (e.g., folate, homocysteine and vitamin B12) and peripheral blood DNA methylation in epileptic patients under treatment with antiepileptic drugs (AEDs) and in healthy controls. METHODS: In this cr...

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Pubblicato in:PLoS One
Autori principali: Ni, Guanzhong, Qin, Jiaming, Li, Hongliang, Chen, Ziyi, Zhou, Yafang, Fang, Ziyan, Chen, Yishu, Zhou, Jueqian, Huang, Min, Zhou, Liemin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410915/
https://ncbi.nlm.nih.gov/pubmed/25915064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125656
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