Promiscuous Actions of Small Molecule Inhibitors of the Protein Kinase D-Class IIa HDAC Axis in Striated Muscle

PKD-mediated phosphorylation of class IIa HDACs frees the MEF2 transcription factor to activate genes that govern muscle differentiation and growth. Studies of the regulation and function of this signaling axis have involved MC1568 and Gö-6976, which are small molecule inhibitors of class IIa HDAC a...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:FEBS Lett
Hlavní autoři: Lemon, Douglas D., Harrison, Brooke C., Horn, Todd R., Stratton, Matthew S., Ferguson, Bradley S., Wempe, Michael F., McKinsey, Timothy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410688/
https://ncbi.nlm.nih.gov/pubmed/25816750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2015.03.017
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky