Promiscuous Actions of Small Molecule Inhibitors of the Protein Kinase D-Class IIa HDAC Axis in Striated Muscle

PKD-mediated phosphorylation of class IIa HDACs frees the MEF2 transcription factor to activate genes that govern muscle differentiation and growth. Studies of the regulation and function of this signaling axis have involved MC1568 and Gö-6976, which are small molecule inhibitors of class IIa HDAC a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:FEBS Lett
Hauptverfasser: Lemon, Douglas D., Harrison, Brooke C., Horn, Todd R., Stratton, Matthew S., Ferguson, Bradley S., Wempe, Michael F., McKinsey, Timothy A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410688/
https://ncbi.nlm.nih.gov/pubmed/25816750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2015.03.017
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge