NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma

Hepatocellular carcinoma (HCC) develops on the background of chronic hepatitis. Leukocytes found within the HCC microenvironment are implicated as regulators of tumour growth. We show that diethylnitrosamine (DEN)-induced murine HCC is attenuated by antibody-mediated depletion of hepatic neutrophils...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Wilson, C. L., Jurk, D., Fullard, N., Banks, P., Page, A., Luli, S., Elsharkawy, A. M., Gieling, R. G., Chakraborty, J. Bagchi, Fox, C., Richardson, C., Callaghan, K., Blair, G. E., Fox, N., Lagnado, A., Passos, J. F., Moore, A. J., Smith, G. R., Tiniakos, D. G., Mann, J., Oakley, F., Mann, D. A.
Format: Artigo
Jezik:Inglês
Izdano: Nature Pub. Group 2015
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410629/
https://ncbi.nlm.nih.gov/pubmed/25879839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7818
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