The rare BRAF VK600-601E mutation as a possible indicator of poor prognosis in rectal carcinoma – a report of a case

BACKGROUND: The BRAF V600E mutation is reportedly associated with inferior survival among colon cancer patients. Here we report a patient with rectal cancer who carried the novel BRAF mutation VK600–601E, which has analogous molecular functions to those of the conventional BRAF mutation V600E, and m...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Med Genet
Hauptverfasser: Mori, Yoshiko, Nagasaka, Takeshi, Mishima, Hideyuki, Umeda, Yuzo, Inada, Ryo, Kishimoto, Hiroyuki, Goel, Ajay, Fujiwara, Toshiyoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Case Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410594/
https://ncbi.nlm.nih.gov/pubmed/25636897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-015-0144-7
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