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Identifying candidate drivers of alcohol dependence-induced excessive drinking by assembly and interrogation of brain-specific regulatory networks

BACKGROUND: A systems biology approach based on the assembly and interrogation of gene regulatory networks, or interactomes, was used to study neuroadaptation processes associated with the transition to alcohol dependence at the molecular level. RESULTS: Using a rat model of dependent and non-depend...

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Détails bibliographiques
Publié dans:Genome Biol
Auteurs principaux: Repunte-Canonigo, Vez, Shin, William, Vendruscolo, Leandro F, Lefebvre, Celine, van der Stap, Lena, Kawamura, Tomoya, Schlosburg, Joel E, Alvarez, Mariano, Koob, George F, Califano, Andrea, Sanna, Pietro Paolo
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410476/
https://ncbi.nlm.nih.gov/pubmed/25886852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0593-5
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