Identifying candidate drivers of alcohol dependence-induced excessive drinking by assembly and interrogation of brain-specific regulatory networks

BACKGROUND: A systems biology approach based on the assembly and interrogation of gene regulatory networks, or interactomes, was used to study neuroadaptation processes associated with the transition to alcohol dependence at the molecular level. RESULTS: Using a rat model of dependent and non-depend...

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Bibliographische Detailangaben
Veröffentlicht in:Genome Biol
Hauptverfasser: Repunte-Canonigo, Vez, Shin, William, Vendruscolo, Leandro F, Lefebvre, Celine, van der Stap, Lena, Kawamura, Tomoya, Schlosburg, Joel E, Alvarez, Mariano, Koob, George F, Califano, Andrea, Sanna, Pietro Paolo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410476/
https://ncbi.nlm.nih.gov/pubmed/25886852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0593-5
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