Identifying candidate drivers of alcohol dependence-induced excessive drinking by assembly and interrogation of brain-specific regulatory networks

BACKGROUND: A systems biology approach based on the assembly and interrogation of gene regulatory networks, or interactomes, was used to study neuroadaptation processes associated with the transition to alcohol dependence at the molecular level. RESULTS: Using a rat model of dependent and non-depend...

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Vydáno v:Genome Biol
Hlavní autoři: Repunte-Canonigo, Vez, Shin, William, Vendruscolo, Leandro F, Lefebvre, Celine, van der Stap, Lena, Kawamura, Tomoya, Schlosburg, Joel E, Alvarez, Mariano, Koob, George F, Califano, Andrea, Sanna, Pietro Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410476/
https://ncbi.nlm.nih.gov/pubmed/25886852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0593-5
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