Discovery and anti-cancer evaluation of two novel non-ATP-competitive FGFR1 inhibitors in non-small-cell lung cancer

BACKGROUND: Fibroblast growth factor receptor 1 (FGFR1) is correlated closely with the occurrence and development of lung cancer. FGFR1 kinase inhibitors have exhibited significant therapeutic effects against non-small-cell lung cancer. Recently, non-ATP competitive FGFR1 inhibitors have attracted e...

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Dettagli Bibliografici
Pubblicato in:BMC Cancer
Autori principali: Wu, Jianzhang, Wei, Tao, Tang, Qinqin, Weng, Bixia, Li, Wulan, Jiang, Xin, Ding, Ting, Li, Xiaokun, Liang, Guang, Cai, Yuepiao, Ji, Jiansong
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410475/
https://ncbi.nlm.nih.gov/pubmed/25880284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1307-9
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