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Mechanistic Studies of Inactivation of Inducible Nitric Oxide Synthase by Amidines
Nitric oxide synthase (NOS) catalyzes the conversion of l-arginine to l-citrulline and nitric oxide. N(5)-(1-Iminoethyl)-L-ornithine (L-NIO), an amidine-containing molecule, is a natural product known to be an inactivator of inducible NOS (iNOS). Because of the presence of the amidine methyl group i...
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| Published in: | Biochemistry |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4410366/ https://ncbi.nlm.nih.gov/pubmed/25811913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00135 |
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