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Antibody catalysis of peptide bond formation.

An antibody generated against a neutral phosphonate diester transition-state (TS not equal to) analog catalyzes the formation of an amide bond between a phenylalanyl amino group and an acyl azide derived from L-alanine. The antibody is selective for L- vs. D-alanine and does not catalyze the hydroly...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Jacobsen, J R, Schultz, P G
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1994
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44102/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8016084/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.13.5888
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