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Deciphering a hexameric protein complex with Angstrom optical resolution

Cryogenic optical localization in three dimensions (COLD) was recently shown to resolve up to four binding sites on a single protein. However, because COLD relies on intensity fluctuations that result from the blinking behavior of fluorophores, it is limited to cases where individual emitters show d...

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Principais autores: Hisham Mazal, Franz-Ferdinand Wieser, Vahid Sandoghdar
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2022-05-01
Colecção:eLife
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Acesso em linha:https://elifesciences.org/articles/76308
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