Celastrol, a Chinese herbal compound, controls autoimmune inflammation by altering the balance of pathogenic and regulatory T cells in the target organ

Inflammation is an integral component of autoimmune arthritis. The balance of pathogenic T helper 17 (Th17) and protective T regulatory (Treg) cells can influence disease severity, and its resetting offers an attractive approach to control autoimmunity. We determined the frequency of Th17 and Treg i...

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Detalhes bibliográficos
Publicado no:Clin Immunol
Main Authors: Astry, Brian, Venkatesha, Shivaprasad H., Laurence, Arian, Christensen-Quick, Aaron, Garzinodemo, Alfredo, Frieman, Matthew B, O’Shea, John J., Moudgil, Kamal D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410084/
https://ncbi.nlm.nih.gov/pubmed/25660987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2015.01.011
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