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Bioreducible Polycations in Nucleic Acid Delivery: Past, Present, and Future Trends

Polycations that are degradable by reduction of disulfide bonds are developed for applications in delivery of nucleic acids. This paper surveys methods of synthesis of bioreducible polycations and discusses current understanding of the mechanism of action of bioreducible polyplexes. Emphasis is plac...

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Detalhes bibliográficos
Publicado no:Macromol Biosci
Main Authors: Oupický, David, Li, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410047/
https://ncbi.nlm.nih.gov/pubmed/24678057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mabi.201400061
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