A versatile reducible polycation-based system for efficient delivery of a broad range of nucleic acids

Synthetic vectors based on reducible polycations consisting of histidine and polylysine residues (HIS RPCs) were evaluated for their ability to deliver nucleic acids. Initial experiments showed that RPC-based vectors with at least 70% histidine content mediated efficient levels of gene transfer with...

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Detalhes bibliográficos
Main Authors: Read, Martin L., Singh, Surjeet, Ahmed, Zubair, Stevenson, Mark, Briggs, Simon S., Oupicky, David, Barrett, Lee B., Spice, Rachel, Kendall, Mark, Berry, Martin, Preece, Jon A., Logan, Ann, Seymour, Leonard W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
Assuntos:
Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140087/
https://ncbi.nlm.nih.gov/pubmed/15914665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni085
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