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A versatile reducible polycation-based system for efficient delivery of a broad range of nucleic acids

Synthetic vectors based on reducible polycations consisting of histidine and polylysine residues (HIS RPCs) were evaluated for their ability to deliver nucleic acids. Initial experiments showed that RPC-based vectors with at least 70% histidine content mediated efficient levels of gene transfer with...

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Détails bibliographiques
Auteurs principaux: Read, Martin L., Singh, Surjeet, Ahmed, Zubair, Stevenson, Mark, Briggs, Simon S., Oupicky, David, Barrett, Lee B., Spice, Rachel, Kendall, Mark, Berry, Martin, Preece, Jon A., Logan, Ann, Seymour, Leonard W.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140087/
https://ncbi.nlm.nih.gov/pubmed/15914665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni085
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