The effects of sigma (σ1) receptor-selective ligands on muscarinic receptor antagonist-induced cognitive deficits in mice

BACKGROUND AND PURPOSE: Cognitive deficits in patients with Alzheimer's disease, Parkinson's disease, traumatic brain injury and stroke often involve alterations in cholinergic signalling. Currently available therapeutic drugs provide only symptomatic relief. Therefore, novel therapeutic s...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Malik, Maninder, Rangel-Barajas, Claudia, Sumien, Nathalie, Su, Chang, Singh, Meharvan, Chen, Zhenglan, Huang, Ren-Qi, Meunier, Johann, Maurice, Tangui, Mach, Robert H, Luedtke, Robert R
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2015
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409904/
https://ncbi.nlm.nih.gov/pubmed/25573298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13076
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