The effects of sigma (σ1) receptor-selective ligands on muscarinic receptor antagonist-induced cognitive deficits in mice

BACKGROUND AND PURPOSE: Cognitive deficits in patients with Alzheimer's disease, Parkinson's disease, traumatic brain injury and stroke often involve alterations in cholinergic signalling. Currently available therapeutic drugs provide only symptomatic relief. Therefore, novel therapeutic s...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Malik, Maninder, Rangel-Barajas, Claudia, Sumien, Nathalie, Su, Chang, Singh, Meharvan, Chen, Zhenglan, Huang, Ren-Qi, Meunier, Johann, Maurice, Tangui, Mach, Robert H, Luedtke, Robert R
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409904/
https://ncbi.nlm.nih.gov/pubmed/25573298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13076
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