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The effects of sigma (σ1) receptor-selective ligands on muscarinic receptor antagonist-induced cognitive deficits in mice

BACKGROUND AND PURPOSE: Cognitive deficits in patients with Alzheimer's disease, Parkinson's disease, traumatic brain injury and stroke often involve alterations in cholinergic signalling. Currently available therapeutic drugs provide only symptomatic relief. Therefore, novel therapeutic s...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Pharmacol
Prif Awduron: Malik, Maninder, Rangel-Barajas, Claudia, Sumien, Nathalie, Su, Chang, Singh, Meharvan, Chen, Zhenglan, Huang, Ren-Qi, Meunier, Johann, Maurice, Tangui, Mach, Robert H, Luedtke, Robert R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BlackWell Publishing Ltd 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409904/
https://ncbi.nlm.nih.gov/pubmed/25573298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13076
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