The effects of sigma (σ1) receptor-selective ligands on muscarinic receptor antagonist-induced cognitive deficits in mice

BACKGROUND AND PURPOSE: Cognitive deficits in patients with Alzheimer's disease, Parkinson's disease, traumatic brain injury and stroke often involve alterations in cholinergic signalling. Currently available therapeutic drugs provide only symptomatic relief. Therefore, novel therapeutic s...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Malik, Maninder, Rangel-Barajas, Claudia, Sumien, Nathalie, Su, Chang, Singh, Meharvan, Chen, Zhenglan, Huang, Ren-Qi, Meunier, Johann, Maurice, Tangui, Mach, Robert H, Luedtke, Robert R
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409904/
https://ncbi.nlm.nih.gov/pubmed/25573298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13076
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