TM-233, a novel analog of 1′-acetoxychavicol acetate, induces cell death in myeloma cells by inhibiting both JAK/STAT and proteasome activities

Although the introduction of bortezomib and immunomodulatory drugs has led to improved outcomes in patients with multiple myeloma, the disease remains incurable. In an effort to identify more potent and well-tolerated agents for myeloma, we have previously reported that 1′-acetoxychavicol acetate (A...

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Библиографические подробности
Опубликовано в: :Cancer Sci
Главные авторы: Sagawa, Morihiko, Tabayashi, Takayuki, Kimura, Yuta, Tomikawa, Tatsuki, Nemoto-Anan, Tomoe, Watanabe, Reiko, Tokuhira, Michihide, Ri, Masaki, Hashimoto, Yuichi, Iida, Shinsuke, Kizaki, Masahiro
Формат: Artigo
Язык:Inglês
Опубликовано: BlackWell Publishing Ltd 2015
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Original Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409888/
https://ncbi.nlm.nih.gov/pubmed/25613668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12616
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