TM-233, a novel analog of 1′-acetoxychavicol acetate, induces cell death in myeloma cells by inhibiting both JAK/STAT and proteasome activities

Although the introduction of bortezomib and immunomodulatory drugs has led to improved outcomes in patients with multiple myeloma, the disease remains incurable. In an effort to identify more potent and well-tolerated agents for myeloma, we have previously reported that 1′-acetoxychavicol acetate (A...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Sagawa, Morihiko, Tabayashi, Takayuki, Kimura, Yuta, Tomikawa, Tatsuki, Nemoto-Anan, Tomoe, Watanabe, Reiko, Tokuhira, Michihide, Ri, Masaki, Hashimoto, Yuichi, Iida, Shinsuke, Kizaki, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409888/
https://ncbi.nlm.nih.gov/pubmed/25613668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12616
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