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Fibroblast Growth Factor 23 Regulates Renal 1,25-Dihydroxyvitamin D and Phosphate Metabolism via the MAP Kinase Signaling Pathway in Hyp Mice

In X-linked hypophosphatemia (XLH) and in its murine homologue, the Hyp mouse, increased circulating concentrations of fibroblast growth factor 23 (FGF-23) are critical to the pathogenesis of disordered metabolism of phosphate (P(i)) and 1,25-dihydroxyvitamin D [1,25(OH)(2)D]. In this study, we hypo...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Ranch, Daniel, Zhang, Martin YH, Portale, Anthony A, Perwad, Farzana
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409871/
https://ncbi.nlm.nih.gov/pubmed/21472778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.401
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