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Stereoselective Pharmacokinetics of Stable Isotope (+/−)-[(13)C]-Pantoprazole: Implications for a Rapid Screening Phenotype Test of CYP2C19 Activity
AIMS: We have previously shown that the (±)-[(13)C]-pantoprazole breath test is a promising noninvasive probe of CYP2C19 activity. As part of that trial, plasma, breath test indices and CYP2C19 (*2, *3 and *17) genotype were collected. Here, we examined whether [(13)C]-pantoprazole exhibits enantios...
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| Veröffentlicht in: | Chirality |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4409653/ https://ncbi.nlm.nih.gov/pubmed/21935988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chir.21011 |
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