RhoGDIβ Inhibits Bone Morphogenetic Protein 4 (BMP4)-induced Adipocyte Lineage Commitment and Favors Smooth Muscle-like Cell Differentiation

The integration of signals involved in deciding the fate of mesenchymal stem cells is largely unknown. We used proteomics profiling to identify RhoGDIβ, an inhibitor of the small G-protein Rho family, as a component that regulates commitment of C3H10T1/2 mesenchymal stem cells to the adipocyte or sm...

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Опубликовано в: :J Biol Chem
Главные авторы: Huang, Hai-Yan, Zhang, Wen-Ting, Jiang, Wen-Yan, Chen, Su-Zhen, Liu, Yang, Ge, Xin, Li, Xi, Dang, Yong-Jun, Wen, Bo, Liu, Xiao-Hui, Lu, Hao-Jie, Tang, Qi-Qun
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2015
Предметы:
Developmental Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409270/
https://ncbi.nlm.nih.gov/pubmed/25778399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.608075
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