RhoGDIβ Inhibits Bone Morphogenetic Protein 4 (BMP4)-induced Adipocyte Lineage Commitment and Favors Smooth Muscle-like Cell Differentiation

The integration of signals involved in deciding the fate of mesenchymal stem cells is largely unknown. We used proteomics profiling to identify RhoGDIβ, an inhibitor of the small G-protein Rho family, as a component that regulates commitment of C3H10T1/2 mesenchymal stem cells to the adipocyte or sm...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Huang, Hai-Yan, Zhang, Wen-Ting, Jiang, Wen-Yan, Chen, Su-Zhen, Liu, Yang, Ge, Xin, Li, Xi, Dang, Yong-Jun, Wen, Bo, Liu, Xiao-Hui, Lu, Hao-Jie, Tang, Qi-Qun
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409270/
https://ncbi.nlm.nih.gov/pubmed/25778399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.608075
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