RhoGDIβ Inhibits Bone Morphogenetic Protein 4 (BMP4)-induced Adipocyte Lineage Commitment and Favors Smooth Muscle-like Cell Differentiation

The integration of signals involved in deciding the fate of mesenchymal stem cells is largely unknown. We used proteomics profiling to identify RhoGDIβ, an inhibitor of the small G-protein Rho family, as a component that regulates commitment of C3H10T1/2 mesenchymal stem cells to the adipocyte or sm...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Huang, Hai-Yan, Zhang, Wen-Ting, Jiang, Wen-Yan, Chen, Su-Zhen, Liu, Yang, Ge, Xin, Li, Xi, Dang, Yong-Jun, Wen, Bo, Liu, Xiao-Hui, Lu, Hao-Jie, Tang, Qi-Qun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409270/
https://ncbi.nlm.nih.gov/pubmed/25778399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.608075
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